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Objective:To investigate the effect of microsurgery by modified pterional approach in the treatment of temporal lobe epilepsy under intraoperative cortical encephalon electricity graph (EEG) monitoring.Methods:The clinical data of 32 patients with temporal lobe epilepsy who were admitted to the Department of Neurosurgery of Shangqiu First People's Hospital from January 2012 to June 2021 were retrospectively analyzed, all patients underwent microsurgical resection of epileptogenic foci by modified pterional approach under cortical EEG monitoring.Results:The postoperative follow-up was from half a year to 6 years. According to the Tan's classification, 25 cases (78.1%(25/32)) of seizures disappeared completely, 3 cases (9.4%(3/32)) of seizures decreased by more than 75%, and 4 cases (12.5%(4/32)) of seizures decreased by more than 50%. Isotropic hemianopia occurred in 1 case (3.1%) after operation, and there was no operative death.Conclusion:Microsurgical resection of epileptogenic foci through modified pterional approach under intraoperative cortical EEG monitoring was a safe and effective method for the treatment of temporal lobe epilepsy.
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Objective:To investigate the correlation of peripheral blood neutrophil-lymphocyte ratio(NLR)and platelet parameters with the prognosis of elderly patients with cerebral hemorrhage.Methods:Clinical data of 80 patients with cerebral hemorrhage admitted to the neurosurgery department of our hospital from January 2017 to July 2019 were retrospectively analyzed.Based on modified Rankin scale scores, they were classified into the good prognosis group(n=49, with modified Rankin scale scores <3 points)and the poor prognosis group(n=31, with modified Rankin scale scores between 3-6 points). General demographic data and results on laboratory indexes including platelet(PLT), platelet distribution width(PDW), mean platelet volume(MPV), absolute lymphocyte count(ALC)and absolute neutrophil count(ANC)were compared between the two groups.Logistic regression analysis was performed to examine the effects of platelet parameters and NLR on the prognosis of elderly patients with cerebral hemorrhage.Results:NLR, PDW and MPV were higher and PLT was lower in the poor prognosis group than in the good prognosis group[(8.89±1.95) vs. (3.13±0.21), (16.75±4.32) % vs.(12.89±2.71) %, (14.82±3.52) % vs. (10.78±1.62) %, (0.37±0.20) % vs.(0.62±0.33) %, t=20.564, 4.918, 6.969 and 4.918, all P<0.001)]. Logistic regression analysis showed that increased levels of NLR, PDW and MPV and decreased levels of PLT were influencing factors for poor prognosis in elderly patients with cerebral hemorrhage( OR=2.759, 2.606, 1.756 and 0.095, all P<0.001). Conclusions:NLR, PDW, MPV and PLT are closely correlated with the prognosis of elderly patients with cerebral hemorrhage and may be used as indexes for prognosis evaluation in these patients.
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Objective To evaluate the efficacy and safety of paclitaxel drug-coated balloons (DCB)in treating acute coronary syndrome in patients with high bleeding risk.Methods A total of 35 inpatients with acute coronary syndrome and high bleeding risk who were treated in our hospital from March 2017 to December 2017 were retrospectively analyzed.The patients were divided into the control group (n=20) treated with normal balloon dilatation and the experimental group (n =15) treated with DCB treatment.The age,major cardiac adverse events(MACE)within 3 months,fatal hemorrhage events,all-cause mortality,attributable mortality,target lesion revascularization rate(TLR),coronary artery stenosis degree before intervention,and coronary artery stenosis degree at once and 3 months after surgery,were used for comparison and for statistical analysis between the control and the experimental group.Results There were no significant differences between the two groups in the indexes as the followings:MACE within 3 months after surgery(25.0％ vs.6.7％,x2 =2.03,P =0.15),fatal hemorrhage events (10.0 ％ vs.6.7 ％,x2 =0.12,P =0.727),all-cause mortality (20.0％ vs.6.7％,x2 =1.24,P =0.27),attributable mortality(10.0％ vs.0.0％,x2 =1.59,P=0.21),TLR(14.3％ vs.0％,x2 =3.08,P =0.08).However,the incidence of fatal hemorrhage and MACE,all-cause mortality,attributable mortality and TLR were relative low in the experimental group (P＞0.05).Conclusions Drug-coated balloon treatment is safe and effective in treating acute coronary syndrome in patients with high bleeding risk.
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Objective To investigate the curative effect of microsurgical treatment of anterior communicating aneurysm via the moeifiee pterional approach uneer combinee neuroelectrophysiological monitoring. Methods The clinical eata of 35 cases of anterior communicating aneurysms were analyzee retrospectively. All the cases were treatee by the microsurgical treatment via moeifiee pterional approach uneer combinee neuroelectrophysiological monitoring. Results All the anterior communicating aneurysms were clippee completely by microsurgical treatment uneer combinee neuroelectrophysiological monitoring. The curative effect was assessee at eischarge accoreing to GOS,inclueing gooe in 29 cases(82. 9% ,29 / 35),moeerate eisability in 4 cases(11. 4% ,4 / 35),severe eisability in 1 case(2. 9% ,1 / 35),eiee in 1 case(2. 9% ,1 / 35). Conclusion Microsurgical treatment of anterior communicating aneurysms via moeifiee pterional approach uneer combinee neuroelectrophysiological monitoring is a safe ane effective methoe,which might be helpful to reeuce the ratio of postoperative eisability ane mortality,ane then improve quality of life for patients.